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CENTRE DE RECHERCHE EN CANCEROLOGIE DE MARSEILLEInstitut Paoli-Calmettes - UMR S 891 / 27 bd Leï Roure / 13009 Marseille
Téléphone : 04-91-75-84-00 / 0491758401
Fax : 04-91-26-03-64
Courriel : francoise.birg@inserm.fr/secretariat.u891@inserm.fr
Equipes Acueil des Masters Contrats Liste des Personnels Publications des 2 dernières années Thèses
| Effectifs |
Enseignants - Chercheurs et Ingénieurs Universitaires : 13
Médecins hospitaliers : 10
Chercheurs et Ingénieurs (INSERM, CNRS, autres) : 40
Personnel Administratif et Technique Universitaire :
Personnel Administratif et Technique (INSERM, CNRS, autres) : 37
Internes : 2
Etudiants (3ème cycle,Post-Doc, Boursiers...) : 36
| Equipes de recherche |
- E1 - IMMUNOLOGIE ET CANCER - (Responsable : Daniel OLIVE)
- E2 - ONCOLOGIE MOLECULAIRE - (Responsable : Daniel BIRNBAUM)
- E3 - POLARITE CELLULAIRE, SIGNALISATION ET CANCER - (Responsable : Jean-Paul BORG)
- E4 - HEMATOPOIESE MOLECULAIRE ET FONCTIONNELLE/SIGNALISATION CELLULAIRE ET MECANISME DE L'ONCOGENESE - (Responsable : Patrice DUBREUIL)
- E5 - RECHERCHE CLINIQUE EN ONCOLOGIE MEDICALE - (Responsable : Christian CHABANNON)
- E6 - MIGRATION DES CELLULES TUMORALES - (Responsable : Ali BADACHE)
- E7 - AVENIR INSERM - BIOLOGIE DES MOLECULES D'ADHERENCE IMPLIQUEES DANS LES INTERACTIONS TUMEUR/HOTE - (Responsable : Michel AURRAND-LIONS)
- E8 - BIOINFORMATIQUE INTEGRATIVE - (Responsable : Ghislain BIDAUT)
- SERVICES COMMUNS DE RECHERCHE - (Responsable : Françoise BIRG)
- Bioinformatique, Biologie structurale et génomique - Aix-Marseille I et II
- Biologie des Cellules Sanguines - Université Paris VII
- Développement et Immunologie - Aix-Marseille II
- Pathologie Humaine : Oncologie : pharmacologie et thérapeutique - Aix-Marseille II
| - | « Maladies neurologiques et maladies psychiatriques (MNP) » - MONTCOUQUIOL Mireille/BORG Jean-Paul - 2008-2011 - ANR |
| - | "EUCAAD": Angiogenic factors and Innovative Therapeutics, FP7 project - HOLMGREN Lars/BORG Jean-Paul - 2008-2010 - EUCAAD (Sweden) |
| - | ANR Blanc Typheffect - MERESSE Stéphane - 2009-2011 - ANR |
| ACQUAVIVA Claire - Contrat jeune chercheur INSERM | 04-91-75-84-08 |
| ADDOU Lynda - Doctorante MESR (BFA) | 04-91-22-34-77 |
| ADELAIDE José - TCH IPC | 04-91-22-35-27 |
| ARCANGELI Marie-Laure - Post-Doctorante Université/FRM | 04-91-75-82-74 |
| ARNOULET Christine - PH IPC | 04-91-22-33-76 |
| AUDEBERT Stéphane - Ingénieur IPC | 04-91-22-33-07 |
| AURRAND-LIONS Michel - Contrat jeune chercheur INSERM | 04-91-75-84-04 |
| BACCINI Michel - TCH INSERM | |
| BADACHE Ali - DR INSERM | 04-91-22-33-33 |
| BAPIN Luc - AJT INSERM | 04-91-75-84-26 |
| BARBARAT Bernadette - TCH IPC | 04-91-22-37-35 |
| BARDIN Florence - TCH INSERM | 04-91-75-82-74 |
| BAUDELET Emilie - IR INSERM/INCa | 04-91-22-33-07 |
| BELOTTI Edwige - Doctorante MR | 04-91-22-34-07 |
| BENSEDDIK Khedidja - Doctorante MESR (BAFA) | 04-91-22-33-33 |
| BERTUCCI François - PU-PH | 04-91-22-35-37 |
| BIDAUT Ghislain - Contrat jeune chercheur INSERM INCA | 04-91-75-84-23 |
| BIRG Françoise - DR INSERM | 04-91-75-84-19 |
| BIRNBAUM Daniel - DR INSERM | 04-91-75-84-07 |
| BLAISE Didier - PU-PH | 04-91-22-35-40 |
| BORG Jean-Paul - PU U2 | 04-91-75-84-03 |
| BORGE Laurence - IR Inserm/ANR | 04-91-75-84-16 |
| BOUTCHAMA Henri - AJT INSERM | 04-91-75-84-26 |
| CABAUD Olivier - IE INSERM | 04-91-75-84-10 |
| CALMELS Boris - PH IPC | 04-91-22-34-63 |
| CARBUCCIA Nadine - AI INSERM | 04-91-22-34-08 |
| CASTELLANO Rémy - TCH IPC | 04-91-75-84-13 |
| CELIS-GUTIERREZ Javier - Doctorant BGI | 04-91-75-84-14 |
| CERVERA Nathalie - TCH IPC | 04-91-22-33-04 |
| CHABANNON Christian - PU-PH IPC | 04-91-22-34-41 |
| CHAFFANET Max - Ingénieur IPC | 04-91-22-34-77 |
| CHAIB Hassiba - Doctorant MR | 04-91-75-84-13 |
| CHAIX Amandine - Doctorante ENS | 04-91-75-84-16 |
| CHARAFE-JAUFFRET Emmanuelle - MCU-PH | 04-91-22-35-40 |
| CHEILLAN Francine - TCH IPC | 04-91-22-34-54 |
| CHETAILLE Bruno - PH IPC | 04-91-22-34-57 |
| CHEVRIER Véronique - IR INSERM | 04-91-75-84-10 |
| COLLETTE Yves - DR INSERM | 04-91-75-84-13 |
| COULIER François - CR INSERM | 04-91-75-84-23 |
| DAOU Pascale - Doctorant | |
| DE SEPULVEDA Paulo - CR INSERM | 04-91-75-84-76 |
| DENTAL Clélia - Doctorante MR | 04-91-75-84-12 |
| DUBREUIL Patrice - DR INSERM | 04-91-75-84-18 |
| DUPREZ ESTELLE - CR CNRS | |
| DUVIVIER Laurence - AI INSERM | 04-91-75-84-00 |
| EXTRA Jean-Marc - PH IPC | 04-91-22-33-02 |
| FERRARI Anthony - TCH IPC | 04-91-22-34-06 |
| FINETTI Pascal - TCH IPC | 04-91-22-43-87 |
| FLORENTIN Jonathan - Doctorant | |
| FOURNIER Gaëlle - Doctorante Université/ LNCC | 04-91-75-84-09 |
| FRONTERA Vincent - Doctorant INSERM/REGION | 04-91-75-82-74 |
| GALINDO Jean-Rémy - TCH IPC | 04-91-75-84-24 |
| GARCIA Maxime - Doctorant | |
| GARZINO Patrick - TCH INSERM | 04-91-75-84-05 |
| GAZON Hélène - Doctorant | |
| GELSI-BOYER Véronique - MCU-PH | 04-91-22-34-47 |
| GENEIX Jeannine - TCH IPC | 04-91-22-44-59 |
| GENRE Dominique - PH IPC | 04-91-22-36-47 |
| GEORGES Coralie - IR Inserm/INCa | 04-91-75-84-17 |
| GERTNER-DARDENNE Julie - Post-Doctorante IPC/INCa | 04-91-22-36-40 |
| GHIDOUCHE Abderrezzak - Doctorant MESR (BFA) | 04-91-22-36-40 |
| GIBIER Patrick - AI INSERM | 04-91-75-84-05 |
| GINESTIER Christophe - CR INSERM | 04-91-22-35-09 |
| GIROUX Valentin - Post-Doctorant Université/FRM | 04-91-75-84-12 |
| GONCALVES Anthony - MCU-PH | 04-91-75-84-09 |
| GONDOIS-REY Françoise - IR | 04-91-75-84-21 |
| GRAVIS Gwenaëlle - PH IPC | 04-91-22-37-40 |
| HIRSCH Ivan - DR INSERM | 04-91-75-84-15 |
| IMBERT Anne-Marie - TCH IPC | 04-91-22-34-37 |
| ISNARDON Daniel - IR IPC | 04-91-75-84-25 |
| JACQUEMIER Jocelyne - PH IPC | 04-91-22-34-57 |
| JOSSELIN Emmanuelle - IR INSERM/INCa | 04-91-75-84-10 |
| JUST-LANDI Sylvaine - TCH IPC | 04-91-22-37-35 |
| KADRA Gaïs - Doctorant/Gouvernement Syrien | 04-91-22-34-07 |
| LAGARDE Arnaud - IR INSERM | 04-91-22-34-06 |
| LALOUM Laurence - TCH INSERM | 04-91-75-84-02 |
| LECOCQ Eric - TCH INSERM | 04-91-75-84-16 |
| LEMBO Frédérique - IE Université/Protis Valor | 04-91-22-33-33 |
| LETARD Sébastien - IR | 04-91-75-84-16 |
| LHOUMEAU Anne-Catherine - Doctorante AP-HM/DRASS | 04-91-22-34-07 |
| LIVRATI Philippe - TCH IPC | 04-91-22-37-35 |
| LOPEZ Marc - IR INSERM | 04-91-75-84-07 |
| MALLET Françoise - TCH IPC | 04-91-22-37-35 |
| MARCHETTO Sylvie - IE INSERM | 04-91-22-33-33 |
| MESSAL Nassima - Doctorante MESR (BFA) | 04-91-22-36-40 |
| MEUNIER Cécile - IR INSERM/INCa | 04-91-22-33-33 |
| MEZIL Lynda - Doctorant | |
| MILLE DELPHINE - TCH INSERM | |
| MOLDAWAN Yvonne - AJT INSERM | 04-91-75-84-26 |
| MONGES Geneviève - MCU-PH | 04-91-22-35-40 |
| MOZZICONACCI Marie-Joëlle - PH IPC | 04-91-22-33-85 |
| NUNES Jacques - CR INSERM | 04-91-75-84-14 |
| OBRADOS Elodie - IR INSERM/INCa | 04-91-75-82-74 |
| OLIVE Daniel - PU-PH | 04-91-75-84-15 |
| OLSCHWANG Sylviane - CR INSERM | 04-91-22-34-06 |
| OPI Sandrine - Post-Doctorant INSERM/ANRS | 04-91-75-84-13 |
| ORLANDUCCI Florence - TCH IPC | 04-91-22-37-35 |
| ORSONI Jean-Christophe - TCH INSERM | 04-91-75-84-05 |
| PASTOR Sonia - TCH INSERM | 04-91-75-84-21 |
| PERROT Eloïse - IR INSERM/INCa | 04-91-22-37-35 |
| PUPPO Francesca - Post-Doctorante IPC/INCa | 04-91-22-33-07 |
| PUVIRAJESINGHE Tania - Post-Doctorant | |
| RAYNAUD Stéphane - Doctorant MR | 04-91-22-33-04 |
| REDORTIER-ODASSO Denise - TRC IPC | 04-91-22-37-28 |
| RESTOUIN Audrey - TCH IPC | 04-91-22-33-33 |
| REY Jérôme - PH IPC | 04-91-22-36-42 |
| ROCHAS Caroline - IE INSERM | 04-91-22-36-46 |
| ROCQUAIN Julien - Doctorant | |
| ROSNET Olivier - CR INSERM | 04-91-75-84-11 |
| ROUBIN Régine - CR INSERM | 04-91-75-84-11 |
| ROULLIER Philippe - Post-Doctorant Université | |
| ROUX Claude - IE INSERM | 04-91-75-82-83 |
| ROVERE-REISS Julie - TCH IPC | 04-91-75-84-01 |
| SABATIER Renaud - Doctorante IPC/AP-HM | 04-91-22-33-33 |
| SALAUN Danièle - AI INSERM | 04-91-22-33-33 |
| SALMI Chanaz - Post-Doctorante INSERM/ARC | 04-91-22-33-33 |
| SANTONI Marie-Josée - CR CNRS | 04-91-22-33-07 |
| SEBBAGH Mickaël - CR INSERM | 04-91-22-34-07 |
| SEDJAI Fatima - Doctorante MR | 04-91-75-84-10 |
| STAHL Olivier - IR INSERM/INCa | 04-91-75-84-23 |
| TERRAZZONI Marie-Paule - Documentaliste IPC | 04-91-22-35-22 |
| THIBULT Marie-Laure - Doctorante MR | 04-91-22-36-40 |
| TOIRON Yves - TCH IPC | 04-91-22-37-76 |
| VEUILLEN Caroline - Doctorante Région/Entreprise | 04-91-22-36-42 |
| VEY Norbert - PU-PH | 04-91-22-35-40 |
| VIENS Patrice - PU-PH | 04-91-22-35-40 |
| VIRET Frédéric - PH IPC | 04-91-22-33-02 |
| VITA Marina - Post-Doctorant | |
| WICINSKI Julien - TCH IPC | 04-91-22-34-08 |
| XERRI Luc - PU-PH | 04-91-22-35-14 |
| ZAMBRANO José Francisco - Visiting | 04-91-22-36-46 |
| ZARUBICA Ana - Post-Doctorant Inserm/FNS | 04-91-75-82-74 |
| Publications des 2 dernières années |
| - | Acquaviva C., Chevrier V., Chauvin Jp., Fournier G., Birnbaum D. And Rosnet O. The centrosomal FOP protein is required for cell cycle progression and survival. Cell Cycle, 2009, 8, 1217-1227. |
| - | Arnaud C, Sebbagh M, Nola S, Audebert S, Bidaut G, Hermant A, Gayet O, Dusetti NJ, Ollendorff V, Santoni MJ, Borg JP, Lécine P. MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cell. FEBS Letters, 2009, 583:2326-2332. |
| - | Arnaud C., Sebbagh M., Nola S., Audebert S., Bidaut G., Hermant A., Santoni M.-J., Borg J.-P., and P. Lécine. MCC, a new interacting protein for Scrib is involved in cell migration. FEBS Letters 2009, 583: 2326-32. |
| - | Bastonero S, Le Priol Y, Armand M, Bernard CS, Reynaud-Gaubert M, Olive D, Parzy D, de Bentzmann S, Capo C, Mege JL. New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis. PLoS One. 2009, 4 : e5357 |
| - | Bechlian D, Honstettre A, Terrier M, Brest C, Malenfant C, Mozziconacci MJ, Chabannon C. RNA extracted from blood samples with a rapid automated procedure is fit for molecular diagnosis or minimal residual disease monitoring in patients with a variety of malignant blood disorders. Biopreservation Biobanking, 2009, 7(2): 123-8 |
| - | Bernard F., Gelsi-Boyer V., Murati A., Giraudier S., Trouplin V., Adelaide J., Rey J., Olschwang S., Vainchenker W., Chaffanet M., Vey N., Mozziconacci Mj. And Birnbaum D. Alterations of the NFIA gene in chronic malignant myeloid diseases. Leukemia, 2009, 23, 583-585. |
| - | Bertucci F., Finetti P., Cervera N., Charafe-Jauffret E., Buttarelli M., Jacquemier J., Chaffanet M., Maraninchi D., Viens P. And Birnbaum D. How different are basal and luminal A breast cancers? Int. J. Cancer, 2009, 124, 1338-1348. |
| - | Bidaut G, Stoeckert CJ Jr. Large scale transcriptome data integration across multiple tissues to decipher stem cell signatures. Methods Enzymol. 2009;467:229-45. |
| - | Bidaut G, Stoeckert CJ. Characterization of unknown adult stem cell samples by large scale data integration and artificial neural networks. Pac Symp Biocomput. 2009:356-67. |
| - | Bidaut G, Stoeckert CJ. Characterization of unknown adult stem cell samples by large scale data integration and artificial neural networks. Proc Pacific Symp Biocomputing, 2009:356-367. |
| - | Bidaut G, Stoeckert CJ. Large scale transcriptome data integration across multiple tissues to decipher stem cell signatures. Methods Enzymol, 2009, 467:229-245. |
| - | Blazkova J, Trejbalova K, Rey F, Halfon P, Philibert P, Guiguen G, Verdin E, Olive D, Van Lint C, Hejnar J, and Hirsch I.. CpG methylation controls reactivation of HIV from latency. PloS Pathog 2009,. 5(8):e1000554. |
| - | Boukarabila H, Saurin A, Batsché E, Mossadegh N, Otte A, Pradel J, Muchardt C, Sieweke M, Duprez E. The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukaemic transformation. Genes Dev, 23 1195-1206. (2009). |
| - | Brandt CS, Baratin M, Yi EC, Kennedy J, Gao Z, Fox B, Haldeman B, Ostrander CD, Kaifu T, Chabannon C, Moretta A, West R, Xu W, Vivier E, Levin SD. The B7 family member B7-H6 is a tumor cell ligand for for the activating Natural Killer cell receptor NKp30 in humans. J Exp Med, 2009, 206, 1495-1503. |
| - | Bremer Tm, Jacquemier J., Charafe-Jauffret E., Viens P., Birnbaum D. And Linke Sp. Prognostic marker profile to assess risk in stage I-III hormone receptor-positive breast cancer patients. Int. J. Cancer, 2009, 124, 896-904. |
| - | Carbuccia N., Murati A., Trouplin V., Brecqueville M., Adelaide J., Rey J., Vainchenker W., Bernard Oa., Chaffanet M., Vey N., Birnbaum D. and Mozziconacci Mj. Mutations of ASXL1 gene in myeloproliferative neoplasms. Leukemia, 2009, 23, 2183-2186. |
| - | Charafe-Jauffret E., Ginestier C., Iovino F., Wicinski J., Cervera N., Finetti P., Hur Mh., Monville F., Dutcher J., Brown M., Viens P., Xerri L., Bertucci F., Stassi G., Dontu G., Birnbaum D. And Wicha M. Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res., 2009, 69, 1302-1313. |
| - | Charafe-Jauffret E, Ginestier C, Iovino F, Wicinski J, Cervera N, Finetti P, Hur MH, Diebel ME, Monville F, Dutcher J, Brown M, Viens P, Xerri L, Bertucci F, Stassi G, Dontu G, Birnbaum D, Wicha MS. Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res. 2009, 69 (4) : 1302-13 |
| - | Charfi S, Marcy M, Bories E, Pesanti C, Caillol F, Giovannini M, Viret F, Robert Delpero J, Xerri L, Monges G. Cystic pancreatic endocrine tumors: an endoscopic ultrasound-guided fine-needle aspiration biopsy study with histologic correlation. Cancer Cytopathol. 2009, 25, 117 (3) : 203-10. |
| - | Chetaille Bruno, François Bertucci, Pascal Finetti, Benjamin Esterni, Aspasia Stamatoullas, Jean Michel Picquenot, Marie Christine Copin, Frank Morschhauser, Olivier Casasnovas, Tony Petrella, Thierry Molina, Anne Vekhoff, Pierre Feugier, Reda Bouabdallah, Daniel Birnbaum, Daniel Olive, And Luc Xerri. Molecular profiling of classical Hodgkin's lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome. Blood, 2009 ;113 : 2765-3775 |
| - | Chetaille B., Bertucci F., Finetti P., Esterni B., Stamatoullas A., Picquenot Jm., Copin Mc., Morschhauser F., Casasnovas O., Petrella T., Molina T., Vekhoff A., Feugier P., Bouabdallah R., Birnbaum D., Olive D. And Xerri L. Molecular profiling of classical Hodgkin's lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome. Blood, 2009, 113, 2765-2775. |
| - | de Lavallade H, Ladaique P, Lemarie C, Fürst S, Faucher C, Blaise D, Chabannon C, Calmels B. Older age does not influence allogeneic peripheral blood stem cell mobilization in a population of mostly Caucasian donors (letter to the Editor). Blood, 2009, 113, 1868-1869. |
| - | Déliot N., Chavent, M., Nourry, C., Lécine, P., Arnaud C., Hermant A., Maigret B*. and Borg J.-P*. Biochemical studies and molecular dynamics simulations of Smad3-Erbin interaction identify a non-classical Erbin PDZ binding. BBRC, 2009, 378: 360-5. (*co-last authors) |
| - | Dubreuil P, Letard S, Ciufolini M, Gros L, Humbert M, Casteran N, Borge L, Hajem B, Lermet A, Sippl W, Voisset E, Arock M, Auclair C, Leventhal P Moussy A And O Hermine. Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting c-Kit. PLoS ONE, 2009, 4(9):e7258 |
| - | Ernkvist M., Luna Persson N., Audebert S., Lécine P., Sinha I., Liu M., Schlueter M., Horowitz A., Aase K., Weide T., Borg J.-P., Majumdar A., and L. Holmgren. The angiomotin polarity protein complex spatially regulates RhoA activity in migrating endothelial cells. (2009) Blood, 113 :244-53. |
| - | Ferrand A., Chevrier V., Chauvin Jp. And Birnbaum D. Ajuba, a new microtubule-associated protein that interacts with BUBR1 and Aurora B at kinetochores in metaphase. Biol. Cell, 2009, 101, 221-235 (selected cover). |
| - | Fiore F., Estebe B., Gibier P., Orsoni Jc., Courbard Jr., Chodosh La., Birnbaum D. And Delapeyriere O. Abnormal mammary gland development in MMTV-CBLC transgenic mouse. In vivo, 2009, 23, 225-228. |
| - | Firaguay, G. and Nunès, J.A. Analysis of signaling events by dynamic phosphoflow cytometry. Science Signaling 2009, 2, pl3. |
| - | Gelsi-Boyer V., Trouplin V., Adelaide J., Bonansea J., Cervera N., Carbuccia N., Olschwang S., Mozziconacci Mj., Chaffanet M., Vey N. And Birnbaum D. The polycomb-associated ASXL1 gene is mutated in myelodysplastic syndromes and chronic myelomonocytic leukemia. Br. J. Haematol., 2009, 145, 788-800. |
| - | Gelsi-Boyer V, Trouplin V, Adélaïde J, Bonansea J, Cervera N, Carbuccia N, Lagarde A, Prébet T, Nezri M, Sainty D, Olschwang S, Xerri L, Chaffanet M, Mozziconacci MJ, Vey N, Birnbaum D. Mutations of polycombassociated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia. Br J Haematol. 2009, 145 (6) : 788-800. |
| - | Gérard A, Ghiotto M, Fos C, Guittard G, Compagno D, Galy A, Lemay S, Olive D, Nunès JA. Dok-4 is a novel negative regulator of T cell activation. J Immunol. 2009, 182 : 7681-9. |
| - | Ginestier C., Wicinski J., Cervera N., Monville F., Finetti P., Bertucci F., Wicha Ms., Birnbaum D. And Charafe-Jauffret E. Retinoid signaling regulates breast cancer stem cell differentiation. Cell Cycle, 2009, 8, 3297- 3302. |
| - | Gobert M., Treilleux I., Bendriss-Vermare N., Bachelot T., Goddard-Leon S., Arfi V., Biota C., Doffin Ac., Durand I., Olive D., Perez S., Pasqual N., Faure C., Ray-Coquard I., Puisieux A., Caux C., Blay Jy. And Ménétrier-Caux C. Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoidinfiltrates surrounding primary breast tumors and lead to an adverse clinical outcome. Cancer Res 2009, 69 : 2000-9. |
| - | Gondois-Rey F, Dental C, Halfon P, Baumert TF, Olive D, Hirsch I. Hepatitis C virus is a weak inducer of interferon alpha in plasmacytoid dendritic cells in comparison with influenza and human herpesvirus type-1. PLoS One 2009, 4: e4319. |
| - | Guittard G, Gérard A, Dupuis-Coronas S, Tronchère H, Mortier E, Favre C, Olive D, Zimmermann P, Payrastre B, Nunès Ja. Cutting edge: Dok-1 and Dok-2 adaptor molecules are regulated by phosphatidylinositol 5-phosphate production in T cells. J Immunol. 2009, 182:3974-8. |
| - | Housseman S, Absi N, Dauzère-Pérès S, Chabannon C, Hofman P. Simulation as a decision support tool. Estimating the impacts of using RFID technologies within biobanks. HealthIn, Proceedings of the International Conference on Health Informatics. 2009, 337-43 |
| - | Hua G., Zhu B., Rosa F., Deblon N., Adelaide J., Kahn-Perles B., Birnbaum D. And Imbert J. A negative feedback regulatory loop associates the tyrosine kinase receptor ERBB2 and the transcription factor GATA4 in breast cancer cells. Mol. Cancer Res., 2009, 7, 402-414. |
| - | Jacquemier J., Charafe-Jauffret E., Monville F., Esterni B., Extra Jm., Houvenaeghel G., Xerri L., Bertucci F. And Birnbaum D. Association of GATA3, P53, Ki67 status and perivascular peritumoral invasion is strongly predictive in luminal breast cancers. Breast Cancer Res., 2009, 11, R23. |
| - | Jacquemier J, Charafe-Jauffret E, Monville F, Esterni B, Extra JM, Houvenaeghel G, Xerri L, Bertucci F, Birnbaum D. Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer. Breast Cancer Res. 2009, 11 (2) : R23. |
| - | Kosmider O., Gelsi-Boyer V., Ciudad M., Racoeur C., Jooste V., Vey N., Quesnel B., Fenaux P., Bastie Jn., Beyne-Rauzy O., Stamatoulas A., Dreyfus F., Ifrah N., De Botton S., Vainchenker W., Bernard Ao, Birnbaum D., Fontenay M. And Solary E. Tet2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia. Haematologica, 2009, 94, 1676-1681. |
| - | Kosmider O., Gelsi-Boyer V., Cheok M., Grabar S., Della Valle V, Picard F, Viguie F, Quesnel B., Beyne-Rauzy O., Solary E., Vey N., Hunault-Berger M., Fenaux P., Mansat-De-Mas V., Delabesse E., Guardolia P., Lacombe C., Vainchenker W., Preudhomme C., Dreyfus B., Bernard Oa., Birnbaum D. And Fontenay M. TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDS). Blood, 2009, 114, 3285-3291. |
| - | Labauge P, Fontaine B, Neau Jp, Bergametti F, Riant F, Blecon A, Marchelli F, Arnoult M, Lannuzel A, Clanet M, Olschwang S, Denier C, Tournier-Lasserve E. Multiple dural lesions mimicking meningiomas in patients with CCM3/PDCD10 mutations. Neurology, 2009, 72: 2044-2046. |
| - | Lemarie C, Bouchet G, Sielleur I, Durand V, Navarro F, Calmels B, Chabannon C. A new single platform to numerate CD34+ cells. Cytotherapy, 2009; 11(6):804-6, 806.e1. |
| - | Li X, Stankovic M, Lee BP, Aurrand-Lions M, Hahn CN, Lu Y, Imhof BA, Vadas MA, Gamble JR. JAM-C induces endothelial cell permeability through its association and regulation of {beta}3 integrins. Arterioscler Thromb Vasc Biol. 2009;29:1200-1206. |
| - | M'hidi Hasni, Marie-Laure Thibult, Bruno Chetaille, Françoise Rey, Reda Bouadallah, Daniel Olive And Luc Xerri . High expression of the inhibitory receptor BTLA in TFH cells and in B-CELL SMALL LYMPHOCYTIC LYMPHOMA /CHRONIC LYMPHOCYTIC LEUKEMIA. Am J Clin Pathol, 2009,132(4):589-96 |
| - | Mohty M, de Lavallade H, El-Cheikh J, Ladaique P, Faucher C, Fürst S, Vey N, Coso D, Stoppa AM, Gastaut JA, Chabannon C, Blaise D. Reduced intensity conditioning allogeneic stem cell transplantation for patients with acute myeloid leukemia : long term results of a "donor" versus "no donor" comparison. Leukemia, 2009, 23(1): 194-6 |
| - | Moreau T, Bardin F, Barlogis V, Le Deist F, Chabannon C, Tonnelle C. Hematopoietic engraftment of XLA bone marrow CD34+ cells in NOG / SCID Mice. Cytotherapy, 2009, 11: 198-205. |
| - | Munro KM, Perreau VM. Current and future applications of transcriptomics for discovery in CNS disease and injury. Neurosignals, 2009;17(4):311-27. |
| - | Murati A., Gervais C., Carbuccia N., Finetti P., Cervera N., Adelaide J., Struski S, Lippert E, Mugneret F, Tigaud I, Penther D., Bastard C., Poppe B., Speleman F., Baranger L., Luquet I., Cornillet-Lefebvre P., Nadal P., Nguyen-Khac F., Perot C., Olschwang S., Bertucci F., Chaffanet M., Lessard M., Mozziconacci Mj. And Birnbaum D. Genome profiling of acute myelomonocytic leukemia: alteration of the MYB locus in MYST3-linked cases. Leukemia, 2009, 23, 85-94. |
| - | Olschwang S, Lasset C, Baert-Desurmont S, Buisine Mp, Wang Q, Hutter P, Rouleau E, Caron O, Bourdon V, Thomas G. Age dependent cancer risk is not different in between MSH2 and MLH1 mutation carriers. J Cancer Epidemiol, 2009, doi:10.1155/2009/791754. |
| - | Parkinson H, Kapushesky M, Kolesnikov N, Rustici G, Shojatalab M, Abeygunawardena N, Berube H, Dylag M, Emam I, Farne A, Holloway E, Lukk M, Malone J, Mani R, Pilicheva E, Rayner TF, Rezwan F, Sharma A, Williams E, Bradley XZ, Adamusiak T, Brandizi M, Burdett T, Coulson R, Krestyaninova M, Kurnosov P, Maguire E, Neogi SG, Rocca-Serra P, Sansone SA, Sklyar N, Zhao M, Sarkans U, Brazma A. ArrayExpress update--from an archive of functional genomics experiments to the atlas of gene expression. Nucleic Acids Res. 2009;37(Database issue):D868-72.5 |
| - | Pasero Christine, Alem Truneh , Daniel Olve. Co-signaling molecules: from immune activation to cancer targeting. Curr Mol Med, 2009 9:911-27. |
| - | Pasero Christine, Bernadette Barbarat, Sylvaine Just-Landi, Alain Bernard, Thérèse Aurranschleinitz, Jérome Rey , Eric Eldering, Alemsedeg Truneh, Régis T Costello And Daniel Olive. A role for HVEM, but not LT R, in LIGHT-induced tumor cell death and chemokine production. Eur J Immunol. 2009, 39 : 2502-14. |
| - | Pradel LC, Mitchell AJ, Zarubica A, Dufort L, Chasson L, Naquet P, Broccardo C, Chimini G. ABCA1 hallmarks tissue macrophages and modulates cytokine-triggered polarisation programs. Eur J Immunol. 2009; 39(8):2270-80. |
| - | Restouin A., Aresta S., Prébet T., Borg J.-P., Badache A. and Y. Collette. A simplified ATP Luminescencebased Motility Assay. Biotechniques, 2009, 47: 871-5. |
| - | Rey Jérôme, Caroline Veuillen, Norbert Vey, Réda Bouabdallah, Daniel Olive. Natural killer and gamma delta T cells in haematological malignancies: enhancing the immune effectors. Trends Mol Medicine, 2009, 15, 275-84 |
| - | Rouleau E, Lefol C, Bourdon V, Coulet F, Noguchi T, Soubrier F, Bieche I, Olschwang S, Sobol H, Lidereau R. Quantitative PCR high-resolution melting (qPCR-HRM) curve analysis, a new approach to simultaneously screen point mutations and large rearrangements: application to MLH1 germline mutations in Lynch syndrome. Hum Mutation, 2009, 30: 867-875. |
| - | Ryser S., Dizin E., Jefford Ce., Delaval B., Gagos S., Christodoulidou A., Krause Kh., Birnbaum D. And Irminger-Finger I. Distinct roles of BARD1 isoforms in mitosis: full length BARD1 mediates Aurora B degradation, cancer-associated BARD1! scaffolds Aurora B and BRCA2. Cancer Res., 2009, 69, 1125-1134. |
| - | Sabatier R., Finetti P., Cervera N., Birnbaum D. And Bertucci F. Gene expression profiling and prediction of clinical outcome in ovarian cancer. Crit. Rev. Oncol. Hematol., 2009, 72, 2 : 98-109 |
| - | Sarrazin S, Mossadegh-Keller, N Fukao T, Mossadegh-Keller, N, Aziz, A, Mourcin, F, Vanhille L, Kelly-Modis L, Kastern P, Chan S, Duprez E, Otto C, Sieweke M. MafB restricts m-CSF dependent Myeloid committment divsions of hematopoietic stem cells. Cell, 138 300-13. (2009). |
| - | Scheiermann C, Colom B, Meda P, Patel NS, Voisin MB, Marrelli A, Woodfin A, Pitzalis C, Thiemermann C, Aurrand-Lions M, Imhof BA, Nourshargh S. Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury. Arterioscler Thromb Vasc Biol. 2009;29:1509-1515. |
| - | Sebbagh M., Santoni M.-J., Hall B., Borg J.-P., and M.A. Schwartz. Regulation of LKB1/STRAD localization and function by E-cadherin. Current Biology 2009, 19: 37-42. |
| - | Shagdarsuren E, Djalali-Talab Y, Aurrand-Lions M, Bidzhekov K, Liehn EA, Imhof BA, Weber C, Zernecke A. Importance of junctional adhesion molecule-C for neointimal hyperplasia and monocyte recruitment in atherosclerosis-prone mice-brief report. Arterioscler Thromb Vasc Biol. 2009;29:1161-1163. |
| - | Tao Y., Dai P., Marchetto S., Xiong W.-C., Borg J.-P., and L. Mei. Erbin regulates NRG1 signaling and myelination. PNAS 2009, 106: 9477-82 |
| - | Tebib J, Mariette X, Bourgeois Pi, Flipo R-M, Gaudin P, Le Loet X, Gineste P, Guy L, Mansfield Cd., Moussy A, Dubreuil P, Hermine O And Sibilia J. Masitinib in the Treatment of DMARD-Refractory Active Rheumatoid Arthritis: Results of a Multicentre, Open-Label, Dose Ranging, Phase 2a Study. Arthritis Research & Therapy, 2009, 11:R95 |
| - | Tonnelle C, Dijon M,Moreau T, Garulli C, Bardin F, Chabannon C. Stage-specific overexpression of the dominant neative Ikaros 6 reveals distinct roles of Ikaros throughout B-cell differentiation. Mol Immunol, 2009, 46, 1739-1746 |
| - | Vire Berengère, Audrey restouin, Daniel Olive, Karin van Lint, Yves Collette. Anti-leukemia activity of MS-275 histone deacetylase inhibitor implicates 4-1BBL/4-1BB immunomodulatory functions. PLoS One. 2009, 4 : e7085. |
| - | Wilkes M.C., Repellin C.E., Hong M., Bracamonte M., Penheiter S.G., J.-P. Borg and E.B. Leof. Erbin and then NF2 tumor suppressor Merlin cooperatively regulate cell-type-specific activation of PAK2 by TGF! . (2009) Developmental Cell, 16: 433-444. |
| - | Zabouo G, Imbert AM, Jacquemier J, Fineti P, Moreau T, Esterni B, Birnbaum D, Bertucci F, Chabannon C. CD146 expression is associated with a poor prognosis in human breast tumors and enhanced motility in breast cancer cell lines. Breast Cancer Res, 2009, 11, R1 |
| - | Zarei S, Schwenter F, Luy P, Aurrand-Lions M, Morel P, Kopf M, Dranoff G, Mach N. Role of GM-CSF signalling in cell-based tumor immunization. Blood. 2009;113:6658-6668. |
| - | Zarubica A, Plazzo AP, Stöckl M, Trombik T, Hamon Y, Müller P, Pomorski T, Herrmann A, Chimini G. Functional implications of the influence of ABCA1 on lipid microenvironment at the plasma membrane: a biophysical study. FASEB J. 2009; 23(6):1775-85 |
| - | Zheng Y., Vertuani S., Nyström S., Audebert S., Meijer I., Tegnebratt T., Borg J.-P., Uhlén P., Majumdar A. and L. Holmgren. AmotL1 controls endothelial polarity and Junction stability during sprouting angiogenesis. Circulation Res. 2009, 105: 260-270 |
| - | Zimmerli C, Lee BP, Palmer G, Gabay C, Adams R, Aurrand-Lions M, Imhof BA. Adaptive immune response in JAM-C-deficient mice: normal initiation but reduced IgG memory. J Immunol. 2009;182:4728-4736. |
| - | Acquaviva C., Gelsi-Boyer V. And Birnbaum D. Myelodysplastic syndromes: lost between two states? Leukemia, 2010, 24, 1-5. |
| - | Bodemer C, O Hermine, F Palmérini, P S. Leventhal, S Hadj-Rabia, Y Yang, L Nasca, A Cohen-Akenine, S Barete, F Feger, M Arock, B Catteau, B Sans, Jf Stalder, F Skowron, L Thomas, G Lorette, P Plantin, P Bordigoni, O Lortholary, Y De Prost, H Sobol, A Moussy, And P Dubreuil. Pediatric mastocytosis is a clonal disease associated with various c-kit mutations. J Invest Dermatol. 2010, 130, 3 : 804-815 |
| - | Borentain P, Colson P, Coso D, Bories E, Charbonnier A, Stoppa AM, Auran T, Loundou A, Motte A, Ressiot E, Norguet E, Chabannon C, Bouabdallah R, Tamalet C, Gérolami R. Clinical and virological factors associated with hepatitis B virus reactivation in HBsAgnegative and anti-HBc antibodies-positive patients undergoing chemotherapy and/or autologous stem cell transplantation for cancer. J Viral Hepat. 2010, 17, 11 : 807-815 |
| - | Carbuccia N., Trouplin V., Gelsi-Boyer V., Murati A., Rocquain J., Adelaide J., Olschwang S., Xerri L., Vey N., Chaffanet M., Birnbaum D. And Mozziconnacci Mj. Mutual exclusion of ASXL1 and NPM1 mutations in a series of acute myeloid leukemias. Leukemia, 2010, 24, 2 : 469-473 |
| - | Chabannon C, Honstettre A, Daufresne LM, Martin PM, Bonnetaud C, Birtwisle-Peyrottes I, Romain S, Achache K, Mery O, Bordonne O, Ducord C, Jacotot L, Vaglio P, d'Arnoux C, Figarella-Branger D, Hofman P, Borg JP, Atger V. [Publication of biological samples collections catalogues by tumor banks.]. Bull Cancer. 2010, 97, 2 : 181-189 |
| - | Chapiro E , Russel L, Lainey E, Kaltenbach S, Ragu C, Della-Valle V, Hanssens K, Macintyre Ea, Radford-Weiss I, Delabesse E, Cavé H, Mercher T, Harrison Cj, Nguyen-Khac F, Dubreuil P And Oa Bernard. Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia. Leukemia, 2010, 24, 3 : 642-645 |
| - | Charafe-Jauffret E., Ginestier C., Iovino F., Tarpin C., Diebel M., Esterni B., Houvenaeghel G., Extra Jm., Bertucci F., Jacquemier J., Xerri L., Dontu G., Stassi G., Xiao Y., Barsky Sh, Birnbaum D., Viens P. And Wicha M. ALDH1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin. Cancer Res., 2010, 16, 45-55. |
| - | Delavallade H., Finetti P., Carbuccia N., Khorashad Js., Charbonnier A., Foroni L., Apperley Jf., Vey N., Bertucci F., Birnbaum D. And Mozziconacci Mj. A gene expression signature of primary resistance to imatinib in chronic myeloid leukemia. Leuk Res., 2010, 34, 254-257. |
| - | Derré Laurent, Jean-Paul Rivals, Camilla Jandus, Sonia Pastor, Donata Rimoldi, Pedro Romero, Olivier Michielin, Daniel Olive, and Daniel E. Speiser Functional inhibition of human tumor-specific CD8 T-cells is associated with BTLA expression and is reversed by CpG based vaccination. J Clin Invest 2010, 120 : 157-67 |
| - | Ginestier C., Liu S., Diebel Me, Korkaya H., Luo M., Brown M., Wicinski J., Cabaud O., Charafe-Jauffret E., Birnbaum D., Guan Jl., Dontu G. and WICHA M. CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts. J. Clin. Invest., 2010, 120, 2 : 485-497 |
| - | Hofman V, Selva E, Chabannon C, Bonnetaud C, Gaziello MC, Bordone O, Gavric-Tanga V, Ilie M, Hofman P. Les biobanques en France: enjeux et contraintes. Rev Francophone Laboratoires, 2010, 418 : 49-54 |
| - | Mohty Anne-Marie, Jean-Jacques Grob, Mohamad Mohty, Marie-Aleth Richard, Daniel Olive, Beatrice Gaugler, Induction of IP-10/CXCL10 secretion as an immunomodulatory effect of low-dose adjuvant interferon-alpha during treatment of melanoma. Immunobiology, 2010, 215, 2 : 113-123 |
| - | Mook S, Knauer M, Bueno-de-Mesquita JM, Retel VP, Wesseling J, Linn SC, Van't Veer LJ, Rutgers EJ. Metastatic Potential of T1 Breast Cancer can be Predicted by the 70-gene MammaPrint Signature. Ann Surg Oncol. 2010, 17, 5 : 1406-1413 |
| - | Prébet T, Ladaique P, Ferrando M, Chabannon C, Faucher C, De Lavallade H, El-Cheikh J, Furst S, Vey N, Stoppa AM, Viens P, Blaise D, Mohty M. Platelet recovery and transfusion needs after reduced intensity conditioning allogeneic peripheral blood stem cell transplantation. Exp Hematol. 2010;38(1):55-60. |
| - | Rahner N, Steinke V, Schlegelberger B, Olschwang S, Eisinger F, Hutter P. Clinical utility genetic card for Lynchsyndrome. Eur J Hum Genet, 2010, doi: 10.1038. |
| - | Sobol H, Georgin-Lavialle S, Grandpeix-Guyodo C, Canioni D, Barete S, Dubreuil P, Lortholary O, Beaugerie L And O Hermine. Gastrointestinal involvement and manifestations in systemic mastocytosis. Inflammatory Bowel Disease, 2010, 16, 7 : 1247-1253 |
| - | Tenan M, Aurrand-Lions M, Widmer V, Alimenti A, Burkhardt K, Lazeyras F, Belkouch MC, Hammel P, Walker PR, Duchosal MA, Imhof BA, Dietrich PY. Cooperative expression of junctional adhesion molecule-C and -B supports growth and invasion of glioma. Glia. 2010; 58(5):524-37. |
| - | Voisset E, Lopez S, Chaix A, George C, Hanssens K, Prebet T, Dubreuil P And P De Sepulveda. Fes kinases are required for oncogenic FLT3 signaling. Leukemia. 2010, 28. |
| - | Voisset E, Lopez S, Chaix A, Vita M, George C, Dubreuil P And De Sepulveda P. Fes kinase participates in KIT-ligand induced chemotaxis. Biochem Biophys Res Commun. 2010, 393, 1 : 174-178 |
| - | Zhang H, V Olschwang S, Yu K. Statistical inference on the penetrances of rare genetic mutations based on a case-family design. Biostatistics 2010, 11, 3 : 519-532 |
| Thèses des 2 dernières années |
| - | YANG Ying - Identification et caractérisation fonctionnelle des mutations du gènes c-Kit dans des pathologies mastocytaires humaines et canines - Université de la Méditerrranée - 17/06/2009 |
| - | PREBET Thomas - Implication du récepteur membranaire PTK7 dans les leucémies aigues myéloïdes de l'adulte - Université de la Méditerranée - 20/10/2009 |
| - | ZAOUI Kossay - Rôle de Memo dans la migration des cellules tumorales et la dynamique des microtubules induites par l'activation du récepteur erbB2 - Université de la Méditerranée - 27/11/2009 |
| - | BEKHOUCHE Ismahane - Caractérisation des altérations moléculaires dans les cancers du sein - Université de la Méditerranée - 02/12/2009 |
| - | MONVILLE Florence - Etude de l'origine cellulaire des Cancers du sein - Université de la Méditerranée - 07/12/2009 |
| - | M'HIDI Hasni - Molécules de coinhibition et lymphopathies malignes - Université de la Méditerranée - 15/12/2009 |
| - | SIRCOULOMB Fabrice - Génomique fonctionnelle des cancers du sein - Université de la Méditerranée - 16/12/2009 |
| - | STUHL/GOURMAND Laetitia - Rôle de naca et de ses partenaires moléculaires dans la differenciation erythroide normale et pathologique des syndrômes myelodysplasiques - Université de la Méditerranée - 30/03/2010 |
| - | CHETAILLE Bruno - Facteurs pronostiques biopathologiques des lymphomes Hodgkiniens : influence du microenvironnement - Université de la Méditerranée - 18/06/2010 |
| - | ROCQUAIN Julien - Recherche de nouvelles cibles moléculaires dans les syndromes myélodysplasiques et leucémies aiguës myéloïdes - Université de la Méditerranée - 29/11/2010 |
| - | HASSANEIN Mohamed - Facteurs prédictifs de mutation germinale BRCA1 dans le cancer du sein héréditaire - Université de la Méditerranée - 16/12/2010 |
| - | BELOTTI Edwige - Caractérisation du récepteur de la polarité planaire Vangl2 dans les cancers du sein - Université de la Méditerranée - 21/12/2010 |
© Faculté de Médecine de Marseill l Mentions légales l Mise à jour du 23 février 2012