Annuaire de la Recherche

 


 La recherche < Les laboratoires de recherche
 EMERGENCE DES PATHOLOGIES VIRALES
       Responsable(s) : DE LAMBALLERIE Xavier


  U.F.R. de Médcine - Site Timone - IRD UMR 190 / 27, boulevard Jean Moulin / 13385 Marseille 05
  Téléphone : 04-91-32-44-20
  Fax : 04-91-32-44-21
  Courriel : xavier.de-lamballerie@univmed.fr

  Equipes    Acueil des Masters    Contrats    Liste des Personnels    Publications des 2 dernières années    Thèses

Effectifs
       
  Enseignants - Chercheurs et Ingénieurs Universitaires :      4
  Médecins hospitaliers :      
  Chercheurs et Ingénieurs (INSERM, CNRS, autres) :      12
  Personnel Administratif et Technique Universitaire :      2
  Personnel Administratif et Technique (INSERM, CNRS, autres) :       9
  Internes :      0
  Etudiants (3ème cycle,Post-Doc, Boursiers...) :      26

Equipes de recherche
Laboratoire d'accueil des Masters

 - Pathologie Humaine : Maladies transmissibles et pathologies tropicales - Aix-Marseille II

Contrats
-Phlebo-MED (Emerging phleboviruses around the Mediterranean) - DE LAMBALLERIE X. - 2009-2011 - ANR MIE
-EVA - European Virus Archive - DE LAMBALLERIE X. - 2009-2012 - Contrat européen
PHRC
-Etiologies virales des fièves estivales dans le sud-est de la France - DE LAMBALLERIE X. - 2009-2011 - AP-HM

Personnels impliqués dans la recherche
  ANDAYI Fred  - Doctorant  04-91-32-44-20
  ARIAS Anna-Maria  - Doctorant  04-91-32-44-20
  ARISTODEMO Marie-Thérèse  - ADT U2  04-91-32-44-20
  BAILLON François  - AI IRD  04-91-32-44-20
  BARONTI Cécile  - Doctorant  04-91-32-44-20
  BARTHELEMY Karine  - ITA AP-HM  04-91-32-44-20
  BECQUART Pierre  - CR IRD  04-91-32-44-20
  BICHAUD Laurence  - Doctorant  04-91-32-44-20
  BUCHILLET Dominique  - CR IRD  04-91-32-44-20
  CARON Mélanie  - Doctorant  04-91-32-44-20
  CHARREL Rémi  - MCU-PH  (HDR)   04-91-32-44-20
  CORTES Audrey  - ATER U2  04-91-32-44-20
  DE LAMBALLERIE Xavier  - PU-PH  (HDR)   04-91-32-44-20
  DECHESSE Reine  - ATER PROTISVALOR  04-91-32-44-20
  DELANGUE Julie  - Doctorant  04-91-32-44-20
  DELOGU Iléna  - Doctorant  04-91-32-44-20
  DESCLOUX Elodie  - Doctorant  04-91-32-44-20
  DUBOT Audrey  - IR IRD  04-91-32-44-20
  FAUCILLON Cécile  - ITA IRD  04-91-32-44-20
  FOURNET Florence  - CR IRD  04-91-32-44-20
  GASQUET Clélia  - Doctorant  04-91-32-44-20
  GILLES Magali  - ATER U2  04-91-32-44-20
  GOULD Ernest  - Chercheur Oxford  (HDR)   04-91-32-44-20
  JEEPHOO Paishan  - Doctorant  04-91-32-44-20
  KUMULUNGUI Brice  - ITA CIRMF  04-91-32-44-20
  LEBLANC Nathalie  - AI IRD  04-91-32-44-20
  LEMASSON Jean-Jacques  - AI IRD  04-91-32-44-20
  LEROY Eric  - DR IRD  (HDR)   04-91-32-44-20
  MAGANGA Gael  - Doctorant  04-91-32-44-20
  MONIER Roland  - TCH U2  04-91-32-44-20
  MORALES Karina  - Doctorant  04-91-32-44-20
  MOUREAU Gregory  - Doctorant  04-91-32-44-20
  NAKARIN Chaikew  - Doctorant  04-91-32-44-20
  NIEMETZKY Natalia  - ITA IRD  04-91-32-44-20
  NIKOGUE Dieudonné  - Doctorant  04-91-32-44-20
  NINOVE Laetitia  - AHU, Doctorant  04-91-32-44-20
  NKOGHE Dieudonné  - Chercheur CIRMF  04-91-32-44-20
  NOUGAIREDE Antoine  - Doctorant  04-91-32-44-20
  OLIVERO Malvina  - ATER U2  04-91-32-44-20
  OLLOMO Benjamin  - Chercheur CIRMF  04-91-32-44-20
  PASTORINO Boris  - IE U2  04-91-32-44-20
  POURRUT Xavier  - IR IRD  04-91-32-44-20
  QUERAT Gilles  - CR INSERM  (HDR)   04-91-32-44-20
  SALEZ Nicolas  - Doctorant  04-91-32-44-20
  SESTON Morgan  - ITA IRD  04-91-32-44-20
  SHAHZAD Malik  - Doctorant  04-91-32-44-20
  SOURIS Marc  - DR IRD  (HDR)   04-91-32-44-20
  TAISUWAN Pahurat  - Doctorant  04-91-32-44-20
  TAN Charlène  - Doctorant  04-91-32-44-20
  THIRION Laurence  - CR IRD  04-91-32-44-20
  WAUQUIER Nadia  - Doctorant  04-91-32-44-20
  YABA Philippe  - ITA CIRMF  04-91-32-44-20
  YAMA Ines  - Doctorant  04-91-32-44-20

Publications des 2 dernières années
-Badiaga S, Richet H, Azas P, Zandotti C, Rey F, Charrel R, Benabdelkader el-H, Drancourt M, Raoult D, Brouqui P. Contribution of a shelter-based survey for screening respiratory diseases in the homeless. Eur J Public Health. 2009, 19(2):157-60.
-Baragatti M, Fournet F, Henry MC, Assi S, Ouedraogo H, Rogier C, Salem G. Social and environmental malaria risk factors in urban areas of Ouagadougou, Burkina Faso. Malar J. 2009, 13;8:13.
-Bell-Sakyi L, Ruzek D, Gould EA. Cell lines from the soft tick Ornithodoros moubata. Exp Appl Acarol. 2009;49(3):209-19.
-Bollati M, Alvarez K, Assenberg R, Baronti C, Canard B, Cook S, Coutard B, Decroly E, de Lamballerie X, Gould EA, Grard G, Grimes JM, Hilgenfeld R, Jansson AM, Malet H, Mancini EJ, Mastrangelo E, Mattevi A, Milani M, Moureau G, Neyts J, Owens RJ, Ren J, Selisko B, Speroni S, Steuber H, Stuart DI, Unge T, Bolognesi M. Structure and functionality in flavivirus NS-proteins: Perspectives for drug design. Antiviral Res. 2009, 27.
-Bollati M, Milani M, Mastrangelo E, de Lamballerie X, Canard B, Bolognesi M. Crystal structure of a methyltransferase from a no-known-vector Flavivirus. Biochem Biophys Res Commun. 2009, 24;382(1):200-4.
-Bollati M, Milani M, Mastrangelo E, Ricagno S, Tedeschi G, Nonnis S, Decroly E, Selisko B, de Lamballerie X, Coutard B, Canard B, Bolognesi M. Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus. J Mol Biol. 2009, 385(1):140-52.
-Brouqui P, Vu Hai V, Nougairede A, Lagier JC, Botelho E, Ninove L, Zandotti C, Charrel RN, de Lamballerie X, Raoult D. Improving the diagnostic efficiency of H1N1 2009 pandemic flu: analysis of predictive clinical signs through a prospective cohort. PLoS Curr Influenza. 2009 Oct 21:RRN1120.
-Chaikaew N, Tripathi NK, Souris M. Exploring spatial patterns and hotspots of diarrhea in Chiang Mai, Thailand. Int J Health Geogr. 2009 Jun 24;8:36.
-Charrel RN, de Lamballerie X. Zoonotic aspects of arenavirus infections. Vet Microbiol. 2009 Aug 28.
-Charrel RN, Moureau G, Temmam S, Izri A, Marty P, Parola P, da Rosa AT, Tesh RB, de Lamballerie X. Massilia virus, a novel Phlebovirus (Bunyaviridae) isolated from sandflies in the Mediterranean. Vector Borne Zoonotic Dis. 2009 Oct;9(5):519-30.
-Chiche L, Forel JM, Roch A, Guervilly C, Pauly V, Allardet-Servent J, Gainnier M, Zandotti C, Papazian L. Active cytomegalovirus infection is common in mechanically ventilated medical intensive care unit patients. Crit Care Med. 2009 Jun;37(6):1850-7.
-Cook S, Moureau G, Harbach RE, Mukwaya L, Goodger K, Ssenfuka F, Gould E, Holmes EC, de Lamballerie X. Isolation of a novel species of flavivirus and a new strain of Culex flavivirus (Flaviviridae) from a natural mosquito population in Uganda. J Gen Virol. 2009 Nov;90(Pt 11):2669-78.
-Cornet JP, Demoraes F, Souris M, Pattamaporn K, Gonzalez JP. Spatial distribution of ticks in Thailand: a Discussion basis for tick-borne virus spread assessment. International Journal of Geoinformatics 5, 1 (2009) 57-62.
-de Lamballerie X, Gould EA. With reference to Mexican flu. Influenza Other Respi Viruses. 2009 3(5):203.
-de Lamballerie X, Ninove L, Charrel RN. Antiviral treatment of chikungunya virus infection. Infect Disord Drug Targets. 2009 Apr;9(2):101-4.
-de Lamballerie X. Essential veterinary education in modern molecular tools for the detection of disease: what veterinarians will need to know about genomics and molecular biology and diagnostics (including bioterrorist weapons) in 2025 ? Rev Sci Tech. 2009 Aug;28(2):657-62.
-Descloux E, Cao-Lormeau VM, Roche C, De Lamballerie X. Dengue 1 diversity and microevolution, French Polynesia 2001-2006: connection with epidemiology and clinics. PLoS Negl Trop Dis. 2009 Aug 4;3(8):e493.
-Flahault A, de Lamballerie X, Hanslik T. Symptomatic infections less frequent with H1N1pdm than with seasonal strains: Antoine Flahault, Xavier de Lamballerie, Camille Pelat, Nicolas Salez, Thomas Hanslik. PLoS Curr Influenza. 2009 Dec 24:RRN1140.
-Forrester NL, Boag B, Buckley A, Moureau G, Gould EA. Co-circulation of widely disparate strains of rabbit haemorrhagic disease virus could explain localised epidemicity in the United Kingdom. Virology. 2009 Oct 10;393(1):42-8.
-Gould EA, Higgs S. Impact of climate change and other factors on emerging arbovirus diseases. Trans R Soc Trop Med Hyg. 2009 Feb;103(2):109-21.
-Günther S, Hoofd G, Charrel R, Röser C, Becker-Ziaja B, Lloyd G, Sabuni C, Verhagen R, van der Groen G, Kennis J, Katakweba A, Machang'u R, Makundi R, Leirs H. Mopeia virus-related arenavirus in natal multimammate mice, Morogoro, Tanzania. Emerg Infect Dis. 2009 Dec;15(12):2008-12.
-Hayasaka D, Nagata N, Fujii Y, Hasegawa H, Sata T, Suzuki R, Gould EA, Takashima I, Koike S. Mortality following peripheral infection with tick-borne encephalitis virus results from a combination of central nervous system pathology, systemic inflammatory and stress responses. Virology. 2009 Jul 20;390(1):139-50.
-Jansson AM, Jakobsson E, Johansson P, Lantez V, Coutard B, de Lamballerie X, Unge T, Jones TA. Structure of the methyltransferase domain from the Modoc virus, a flavivirus with no known vector. Acta Crystallogr D Biol Crystallogr. 2009 Aug;65(Pt 8):796-803.
-Khasnatinov MA, Ustanikova K, Frolova TV, Pogodina VV, Bochkova NG, Levina LS, Slovak M, Kazimirova M, Labuda M, Klempa B, Eleckova E, Gould EA, Gritsun TS. Non-hemagglutinating flaviviruses: molecular mechanisms for the emergence of new strains via adaptation to European ticks. PLoS One. 2009 Oct 5;4(10):e7295.
-Leparc-Goffart I, Baragatti M, Temmam S, Tuiskunen A, Moureau G, Charrel R, de Lamballerie X. Development and validation of real-time one-step reverse transcription-PCR for the detection and typing of dengue viruses. J Clin Virol. 2009 May;45(1):61-6.
-Leroy EM, Epelboin A, Mondonge V, Pourrut X, Gonzalez JP, Muyembe-Tamfum JJ, Formenty P. Human Ebola outbreak resulting from direct exposure to fruit bats in Luebo, Democratic Republic of Congo, 2007. Vector Borne Zoonotic Dis. 2009 Dec;9(6):723-8.
-Leroy EM, Nkoghe D, Ollomo B, Nze-Nkogue C, Becquart P, Grard G, Pourrut X, Charrel R, Moureau G, Ndjoyi-Mbiguino A, de Lamballerie X. Concurrent chikungunya and dengue virus infections during simultaneous outbreaks, Gabon, 2007. Emerg Infect Dis. 2009 Apr;15(4):591-3.
-Makuwa M, Mintsa-Ndong A, Souquière S, Nkoghé D, Leroy EM, Kazanji M. Prevalence and molecular diversity of hepatitis B virus and hepatitis delta virus in urban and rural populations in northern Gabon in central Africa. J Clin Microbiol. 2009 Jul;47(7):2265-8.
-Malet H, Coutard B, Jamal S, Dutartre H, Papageorgiou N, Neuvonen M, Ahola T, Forrester N, Gould EA, Lafitte D, Ferron F, Lescar J, Gorbalenya AE, de Lamballerie X, Canard B. The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket. J Virol. 2009 Jul;83(13):6534-45.
-Ninove L, Domart Y, Vervel C, Voinot C, Salez N, Raoult D, Meyer H, Capek I, Zandotti C, Charrel RN. Cowpox virus transmission from pet rats to humans, France. Emerg Infect Dis. 2009 May;15(5):781-4.
-Ninove L, Parola P, Baronti C, de Lamballerie X, Gautret P, Doudier B, Charrel RN. Dengue virus type 3 infection in traveler returning from west Africa. Emerg Infect Dis. 2009 Nov;15(11):1871-2.
-Nisii C, Castilletti C, Di Caro A, Capobianchi MR, Brown D, Lloyd G, Gunther S, Lundkvist A, Pletschette M, Ippolito G; Euronet-P4 Group. The European network of Biosafety-Level-4 laboratories: enhancing European preparedness for new health threats. Clin Microbiol Infect. 2009 Aug;15(8):720-6.
-Nougairede A, Ninove L, Zandotti C, de Lamballerie X, Gazin C, Drancourt M, La Scola B, Raoult D, Charrel RN. Point of Care strategy for rapid diagnosis of novel A/H1N1 influenza virus. PLoS Curr Influenza. 2009 Sep 21:RRN1039.
-Ollomo B, Durand P, Prugnolle F, Douzery E, Arnathau C, Nkoghe D, Leroy E, Renaud F. A new malaria agent in African hominids. PLoS Pathog. 2009 May;5(5):e1000446.
-Pages F, Peyrefitte Cn, Toung Mve M, Jarjaval F, Brisse S, Iteman I, Gravier P, Nkoghe D, Grandadam M. Aedes albopictus mosquito changed the feature of Chikungunya fever in Gabon. PLoS ONE 2009; 4(3):e4691
-Panning M, Charrel RN, Donoso Mantke O, Landt O, Niedrig M, Drosten C. Coordinated implementation of chikungunya virus reverse transcription-PCR. Emerg Infect Dis. 2009 Mar;15(3):469-71.
-Pastorino B, Boucomont-Chapeaublanc E, Peyrefitte CN, Belghazi M, Fusaï T, Rogier C, Tolou HJ, Almeras L. Identification of cellular proteome modifications in response to West Nile virus infection. Mol Cell Proteomics. 2009 Jul;8(7):1623-37.
-Pourrut X, Robert V. [Absence of plasmodial infection among wild monkeys in Northern Senegal?]. Bull Soc Pathol Exot. 2009 Feb;102(1):17-8.
-Pourrut X, Souris M, Towner JS, Rollin PE, Nichol ST, Gonzalez J-P, Leroy EM Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus BMC infect. Dis. 2009; 28(9): 159-169
-Roca Y, Baronti C, Revollo RJ, Cook S, Loayza R, Ninove L, Fernandez RT, Flores JV, Herve JP, de Lamballerie X. Molecular epidemiological analysis of dengue fever in Bolivia from 1998 to 2008. Vector Borne Zoonotic Dis. 2009 Jun;9(3):337-44.
-Ruzek D, Salát J, Palus M, Gritsun TS, Gould EA, Dyková I, Skallová A, Jelínek J, Kopecký J, Grubhoffer L. CD8+ T-cells mediate immunopathology in tick-borne encephalitis. Virology. 2009 Feb 5;384(1):1-6.
-Tuaillon E, Valea D, Becquart P, Tabaa YA, Meda N, Bollore K, Van de perre P, and Vendrell J-P. Human milk derived B cells: a highly activated switched memory cell population primed to secrete antibodies. J Immunol 2009; 182(11):7155-62.
-Tun-Lin W, Lenhart A, Nam VS, Rebollar-Téllez E, Morrison AC, Barbazan P, Cote M, Midega J, Sanchez F, Manrique-Saide P, Kroeger A, Nathan MB, Meheus F, Petzold M. Reducing costs and operational constraints of dengue vector control by targeting productive breeding places: a multi-country non-inferiority cluster randomized trial. Trop Med Int Health. 2009 Sep;14(9):1143-53.
-Vallée J, Dubot-Pérès A, Ounaphom P, Sayavong C, Bryant JE, Gonzalez JP. Spatial distribution and risk factors of dengue and Japanese encephalitis virus infection in urban settings: the case of Vientiane, Lao PDR. Trop Med Int Health. 2009 Sep;14(9):1134-42.
-Wauquier N, Becquart P, GGasquet C, Leroy EM. Immunoglobulin G in Ebola outbreak survivors, Gabon. Emerg Infect Dis. 2009 Jul;15(7):1136-7.
-Wurtz N, Pastorino B, Almeras L, Briolant S, Villard C, Parzy D. Expression and biochemical characterization of the Plasmodium falciparum protein kinase A catalytic subunit. Parasitol Res. 2009 Jun;104(6):1299-305.
-Becquart P, Wauquier N, Mahlakõiv T, Nkoghe D, Padilla C, Souris M, Ollomo B, Gonzalez JP, De Lamballerie X, Kazanji M, Leroy EM. High prevalence of both humoral and cellular immunity to Zaire ebolavirus among rural populations in Gabon. PLoS One. 2010 Feb 9;5(2):e9126.
-Gould EA, Coutard B, Malet H, Morin B, Jamal S, Weaver S, Gorbalenya A, Moureau G, Baronti C, Delogu I, Forrester N, Khasnatinov M, Gritsun T, de Lamballerie X, Canard B. Understanding the alphaviruses: Recent research on important emerging pathogens and progress towards their control. Antiviral Res. 2010, 16, 12 : 1702-1704
-Grard G, Moureau G, Charrel RN, Holmes EC, Gould EA and de Lamballerie X. Genomics and evolution of Aedes-borne flaviviruses J Gen Virol. 2010; 91: 87 – 94
-Moureau G, Ninove L, Izri A, Cook S, de Lamballerie X, Charrel RN. Flavivirus RNA in Phlebotomine Sandflies. Vector Borne Zoonotic Dis. 2010, 10, 2 : 195-197
-Ninove L, Gazin C, Gould EA, Nougairede A, Flahault A, Charrel RN, Zandotti C, de Lamballerie X. A Simple Method for Molecular Detection of Swine-Origin and Human-Origin Influenza A Virus. Vector Borne Zoonotic Dis. 2010, 10, 3 : 237-240
-Nougairede A, Ninove L, Zandotti C, de Lamballerie X, Gazin C, Drancourt M, La Scola B, Raoult D, Charrel RN. Point of Care Strategy for Rapid Diagnosis of Novel A/H1N1 Influenza Virus. PLoS One. 2010 Feb 17;5(2):e9215.
-Nougairede A, Ninove L, Zandotti C, Thiberville SD, Gazin C, Scola BL, Charrel RN, de Lamballerie X. Interim report on A/H1N1 Influenza Virus pandemic in Marseille, France, April-November 2009. Clin Microbiol Infect. 2010, 16, 4 : 322-325
-Nougairède A, Ninove L, Zandotti C, Salez N, Mantey K, Resseguier N, Gazin C, Raoult D, Charrel RN, de Lamballerie X. Novel Virus Influenza A (H1N1sw) in South-Eastern France, April-August 2009. PLoS One. 2010 Feb 17;5(2):e9214.
-Paupy C, Ollomo B, Moutailler S, Rousset D, Kamgang B, Demanou M, Hervé J-P, Leroy E, Simard F. Comparative role of Aedes albopictus and Aedes aegypti in dengue and chikungunya emergence in Central Africa Vector-Borne and Zoonotic Diseases. 2010, 10, 3 : 259-266
-Rouet F, Foulongne V, Viljoen J, Steegen K, Becquart P, Valéa D, Danaviah S, Segondy M, Verhofstede C, Van de Perre P; for the WHO/ANRS 1289 Kesho Bora Study Group. Comparison of the Generic HIV Viral Load((R)) assay with the Amplicor HIV-1 Monitor v1.5 and Nuclisens HIV-1 EasyQ((R)) v1.2 techniques for plasma HIV-1 RNA quantitation of non-B subtypes: The Kesho Bora preparatory study. J Virol Methods. 2010, 163, 2 : 253-257
-Zhioua E, Moureau G, Chelbi I, Ninove L, Bichaud L, Derbali M, Champs M, Cherni S, Salez N, Cook S, de Lamballerie X, Charrel RN. Punique virus, a novel phlebovirus, related to Sandfly fever Naples virus, isolated from sandflies collected in Tunisia. J Gen Virol. 2010, 91, 5 : 1275-1283

Thèses des 2 dernières années
-BARONTI Cécile - Etude de Flavivirus : Epidémiologie moléculaire en Bolivie et Analyse de leur interaction sur la réponse interféron dépendante du TLR3 - Université de la Méditerranée - 08/06/2010
© Faculté de Médecine de Marseill l Mentions légales l Mise à jour du 23 février 2012