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INSTABILITE DU GENOME ET CANCEROGENESECNRS - UPR 9003 / 31, chemin Joseph Aiguier / 13009 MARSEILLE
Téléphone : 04-91-16-40-00
Fax : 04-91-16-40-00
Courriel :
Equipes Acueil des Masters Contrats Liste des Personnels Publications des 2 dernières années Thèses
| Effectifs |
Enseignants - Chercheurs et Ingénieurs Universitaires : 1
Médecins hospitaliers : 8
Chercheurs et Ingénieurs (INSERM, CNRS, autres) : 16
Personnel Administratif et Technique Universitaire :
Personnel Administratif et Technique (INSERM, CNRS, autres) : 3
Internes : 0
Etudiants (3ème cycle,Post-Doc, Boursiers...) : 8
| Equipes de recherche |
- E1-Tolérance des dommages du génome - (Responsable : Robert FUCHS)
- E2-Télomères, chromatine et surveillance moléculaire - (Responsable : Vincent GELI)
- E3-Contrôle des Endonucléases Structure-Spécifiques - (Responsable : Pierre-Henri GAILLARD)
- E4-Contrôle cycle cellulaire : CDK rôle et mode d'action - (Responsable : Eric BAILLY)
- E5-Réparation des cassures double brin - (Responsable : Mauro MODESTI)
- E6-Recombinaison et dynamique du génome - (Responsable : Bertrand LLORENTE)
- E7-Service Commun Recherche - (Responsable : Robert FUCHS)
- Développement et Immunologie - Aix-Marseille II
- Pathologie Humaine : Oncologie : pharmacologie et thérapeutique - Aix-Marseille II
| ACQUAVIVA Laurent - Doctorant | 04-91-16-40-00 |
| ARAGNOL Denise - PU | 04-91-16-40-00 |
| BAILLY Eric - CR INSERM | 04-91-16-40-00 |
| CHARIFI Ferose - PH CNRS INCa | 04-91-16-40-00 |
| CORDA Yves - CR CNRS | 04-91-16-40-00 |
| COULON Stéphane - PH ANR | 04-91-16-40-00 |
| DE LA ROCHE SAINT ANDRE Christophe - CR CNRS | 04-91-16-40-00 |
| FAURE Virginie - Post-Doctorant | 04-91-16-40-00 |
| FUCHS Robert - DR CNRS | 04-91-16-40-00 |
| FUJII Shongo - IR CNRS | 04-91-16-40-00 |
| GABET Anne-Sophie - Post-Doctorant | 04-91-16-40-00 |
| GAILLARD Pierre-Henri - CR CNRS | 04-91-16-40-00 |
| GELI Vincent - DR CNRS | 04-91-16-40-00 |
| GON Stéphanie - CR CNRS | 04-91-16-40-00 |
| GUERVILLY Christophe - PH ARC | 04-91-16-40-00 |
| HARDY Julien - Doctorant | 04-91-16-40-00 |
| ISOGAWA Asako - IR CNRS | 04-91-16-40-00 |
| JOURQUIN Frédéric - IE CNRS | |
| KHDAROO Basheer - PH ATIP | 04-91-16-40-00 |
| LLORENTE Bertrand - CR CNRS | 04-91-16-40-00 |
| LUCIANO Pierre - CR CNRS | 04-91-16-40-00 |
| MAESTRONI Laetitia - Doctorant | 04-91-16-40-00 |
| MAZON-BUSQUETS Gérard - Post-Doctorant | 04-91-16-40-00 |
| MODESTI Mauro - DR CNRS | 04-91-16-40-00 |
| OREAL Vincent - Doctorant | 04-91-16-40-00 |
| PAGES Frédéric - PH ARC | |
| PALUD Adeline - PH ANR | 04-91-16-40-00 |
| PHILIPPIN Gaelle - IE CNRS | 04-91-16-40-00 |
| PINET Isabelle - TCH CNRS | 04-91-16-40-00 |
| POINSIGNON Catherine - PH CEFIC | 04-91-16-40-00 |
| ROCHA Walter - Post-Doctorant | 04-91-16-40-00 |
| SCAGLIONE Sarah - TCH FRM | 04-91-16-40-00 |
| SIMON Marie-Noëlle - CR CNRS | 04-91-16-40-00 |
| TISSIER Agnes - CR INSERM | 04-91-16-40-00 |
| TORRES Martine - ADT CNRS | 04-91-16-40-00 |
| VERGNES Alexandra - PH AICR | 04-91-16-40-00 |
| Publications des 2 dernières années |
| - | Abdallah P*, Luciano P*, Eckert-Boulet N, Germann SM, Lisby M, Géli V, Gilson E#, and Teixeira T A two step model for senescence triggered by a single critically short telomere *Co-first author, #Corresponding author Nat Cell Biol. 2009, 8 : 988-93. |
| - | Bichara M, Fuchs RP, Cordonnier A, Lambert IB. Preferential post-replication repair of DNA lesions situated on the leading strand of plasmids in Escherichia coli. Mol Microbiol 2009,71:305-314. |
| - | Borde V, Robine N, Lin W, Bonfils S, Géli V* and Nicolas A*. Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites EMBO J. 2009, 26 : 99-11. |
| - | Fekairi S, Scaglione S, Chahwan C, Taylor ER, Tissier A, Coulon S, et al. Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases. Cell 2009,138:78-89. |
| - | Fujii S, Fuchs RP. Biochemical basis for the essential genetic requirements of RecA and the beta-clamp in Pol V activation. Proc Natl Acad Sci U S A 2009,106:14825-14830. |
| - | Halbach A, Zhang H, Wengi A, Jablonska Z, Gruber IM, Halbeisen RE, Dehé PM, Kemmeren P, Holstege F, Géli V, Gerber AP, Dichtl B. Cotranslational assembly of the yeast SET1C histone methyltransferase complex. EMBO J. 2009, 28 : 2959-70. |
| - | Khadaroo B, Teixeira T, Luciano P, Eckert-Boulet N, Germann SM, Abdallah P, Gilson E, Géli V# and Lisby M. Sumoylation and chromosome end structure determine the DNA damage response to short telomeres #corresponding author Nat Cell Biol. 2009, 8 : 980-87. |
| - | Lisby M & Géli V . The DNA damage response at telomeres. Cell Cycle. 2009. 8:3617-8 |
| - | Llorente B. and Modesti M. Fungal BRCA2 ortholog Brh2 Brings 5' end strand invasion back on stage. Mol Cell. 2009, 25;36(4):539-40. |
| - | Llorente, B. and Modesti, M. Fungal BRCA2 ortholog Brh2 brings the 5' end tailed duplex back on stage. Mol Cell 2009, 36(4):539-540. |
| - | Mazon G, Philippin G, Cadet J, Gasparutto D, Fuchs RP. The alkyltransferase-like ybaZ gene product enhances nucleotide excision repair of O(6)-alkylguanine adducts in E. coli. DNA Repair (Amst) 2009,8:697-703. |
| - | Samira Fekairi, Sarah Scaglione, Charly Chahwan, Ewan R. Taylor, Agnès Tissier, Stéphane Coulon, Meng-Qiu Dong, Cristian Ruse, John R. Yates III, Paul Russell, Robert P. Fuchs, Clare H. McGowan, Pierre-Henri L. Gaillard Human SLX4 is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases 2009 Cell 138 (1) pp. 78-89 |
| - | van Mameren J, Gross P, Farge G, Hooijman P, Modesti M, Falkenberg M, Wuite GJ, Peterman EJ. Unraveling the structure of DNA during overstretching by using multicolor, single-molecule fluorescence imaging. Proc Natl Acad Sci U S A. 2009, 27;106(43):18231-18236. |
| - | van Mameren, J., Modesti, M., Kanaar, R., Wyman, C., Peterman, E.J. and Wuite, G.J. Counting RAD51 proteins disassembling from nucleoprotein filaments under tension. Nature. 2009, 457:745-748. |
| - | Wagner J, Etienne H, Fuchs RP, Cordonnier A, Burnouf D. Distinct beta-clamp interactions govern the activities of the Y family PolIV DNA polymerase. Mol Microbiol 2009,74:1143-1151. |
| - | Wu PY, Frit P, Meesala S, Dauvillier S, Modesti M, Andres SN, Huang Y, Sekiguchi J, Calsou P, Salles B, Junop MS. Structural and Functional Interaction between the Human DNA Repair Proteins DNA Ligase IV and XRCC4. Mol Cell Biol. 2009, 29(11):3163-3172. |
| - | Morillo-Huesca M., Maya D. ,Muñoz-Centeno MC, Singh R.K., Oreal V. , Reddy GU, Liang, Géli V. , Gunjan, A., Chavez, S. FACT prevents the accumulation of free histones from transcribed chromatin and a subsequent cell cycle delay in G1. PLOS Genetics 2010, 6, 5 |
| - | Ramasubramanyan S, Coulon S, Fuchs RP, Lehmann AR, Green CM. Ubiquitin-PCNA fusion as a mimic for mono-ubiquitinated PCNA in Schizosaccharomyces pombe. DNA Repair (Amst) 2010, 9, 7 : 777-784 |
| - | Rodríguez-Gil A, García-Martínez, JL Pelechano V, de la Cruz Muñoz-Centeno M, Geli V, Pérez-Ortín JE and Chávez S. The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors. Nucleic Acids .Res. 2010. 38, 14 : 4651-4664 |
| - | Schmutz V, Janel-Bintz R, Wagner J, Biard D, Shiomi N, Fuchs RP, Cordonnier AM. Role of the ubiquitin-binding domain of Pol? in Rad18-independent translesion DNA synthesis in human cell-free extracts. Nucleic Acids Res 2010, 38, 19 : 6456-6465 |
| - | Tissier A, Janel-Bintz R, Coulon S, Klaile E, Kannouche P, Fuchs RP, Cordonnier A. Crosstalk between replicative and translesional DNA polymerases: PDIP38 interacts directly with Pol?. DNA Repair (Amst) 2010, 9, 8 : 922-928 |
| Thèses des 2 dernières années |
| - | OREAL Vincent - Rôle de l'histoire methyl transferase Set1 sur la fixation à l'ADN des facteurs de transcription - Université de la Méditerranée - 01/07/2010 |
© Faculté de Médecine de Marseill l Mentions légales l Mise à jour du 23 février 2012