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SERVICE DE PEDIATRIE ET D'HEMATOLOGIE ONCOLOGIE PEDIATRIQUEC.H.U. Timone / 27, boulevard Jean Moulin / 13385 Marseille 5
Téléphone : 04-91-38-67-78
Fax : 04-91-38-49-89
Courriel : gerard.michel@ap-hm.fr
Equipes Acueil des Masters Contrats Liste des Personnels Publications des 2 dernières années Thèses
| Effectifs |
Enseignants - Chercheurs et Ingénieurs Universitaires : 5
Médecins hospitaliers : 8
Chercheurs et Ingénieurs (INSERM, CNRS, autres) :
Personnel Administratif et Technique Universitaire :
Personnel Administratif et Technique (INSERM, CNRS, autres) :
Internes : 2
Etudiants (3ème cycle,Post-Doc, Boursiers...) : 7
| Equipes de recherche |
- HEMOPATHIES MALIGNES ( C. CURTILLET, F. BERNARD) - (Responsable : Gérard MICHEL )
- GREFFES DE CELLULES SOUCHE HEMATOPOEITIQUE(CSH) ( C. GALAMBRUN, C. COZE) - (Responsable : Gérard MICHEL )
- HEMOGLOBINOPATHIES - (Responsable : Isabelle THURET)
- MALADIES HEMORRAGIQUES CONSTITUTIONNELLES - (Responsable : Hervé CHAMBOST)
- INFECTIONS VIH - (Responsable : Isabelle THURET)
- DEFICITS IMMUNITAIRES CONSTITUTIONNELS (G. MICHEL) - (Responsable : Vincent BARLOGIS)
- ONCOLOGIE PEDIATRIQUE (C. COZE, N. ANDRE, A. ROME, A. VERSCHUUR, J.L. BERNARD, E. MOBIKIDS, A. ROME, - (Responsable : Jean-Claude GENTET )
| - | SFCE-Metro 01 : étude de phase II de chimiothérapie métronomique associant celecoxib-methotrexate-vinblastine-cyclophosphamide chez les enfants porteurs d'une tumeur solide en progression. - Arnauld VERSCHUUR - 2009 - Enfants et Santé |
| PHRC | |
| - | Cohorte prospective multi-centrique des Leucémies de l'Enfant et Adolescent : Déterminants de l'état de santé et de la qualité de vie des patients après traitement d'une leucémie aiguë de l'enfance - LEA - Pascal AUQUIER Gérard MICHEL - 2010 - PHRC National |
| - | SFCE-Metro 01 : étude de phase II de chimiothérapie métronomique associant celecoxib-methotrexate-vinblastine-cyclophosphamide chez les enfants porteurs d'une tumeur solide en progression. - Arnauld VERSCHUUR - 2010 - PHRC National |
| - | Etude des microparticules circulantes d'origine érythrocytaire et plaquettaire dans les bêtathalassémies - Isabelle THURET - 2009 - PHRC National |
| - | Etude prospective randomisée multicentrique comparant les résultats de la greffe d'une versus deux unités de sang placentaire chez des patients âges de moins de 35 ans atteints de leucémie aigue en rémission - Gérard MICHEL - 2009 - PHRC National |
| - | Evaluation de l'application de recommandations de prophylaxie précoce et identification de facteurs déterminants chez les enfants hémophiles A et B sévères de la cohorte nationale « Réseau FranceCoag » - Hervé CHAMBOST - 2009 - PHRC National |
| ANDRE Nicolas - PH Contractuel | 04-91-38-68-19 |
| BARLOGIS Vincent - PH | 04-91-38-67-78 |
| BERNARD Fanette - CCA | 04-91-38-67-78 |
| BERNARD Jean-Louis - PU-PH | 04-91-38-68-19 |
| CHAMBOST Hervé - PU-PH | 04-91-38-67-78 |
| COZE Carole - MCU-PH | 04-91-38-68-19 |
| CURTILLET Catherine - PH | 04-91-38-67-78 |
| GALAMBRUN Claire - PH | 04-91-38-67-78 |
| GENTET Jean-Claude - PH | 04-91-38-68-19 |
| MICHEL Gérard - PU-PH | 04-91-38-67-78 |
| ROME Angélique - PH | 04-91-38-68-19 |
| THURET Isabelle - PH | 04-91-38-67-78 |
| VERSCHUUR Arnauld - PH | 04-91-38-68-19 |
| Publications des 2 dernières années |
| - | André N, Pasquier E, Verschuur A, Sterba J, Gentet JC, Rössler J. Metronomic chemotherapy in pediatric oncology: hype or hope?. Arch Pediatr. 2009;16:1158-65 |
| - | André N, Pasquier E. Intermittent androgen blockade in prostate cancer Nature Clinical Practice Oncology. 2009;6:E1 |
| - | André N, Pasquier E. For cancer, seek and destroy or live and let live ? Nature. 2009;460:324 |
| - | André N, Verschuur A, Rome A, Coze C, Gentet JC, Padovani L. Low dose cytarabine in patients with relapsed or refractory Ewing sarcoma. Pediatr Blood Cancer. 2009;53:238 |
| - | Badens C, Thuret I. Beta-thalassemia major: what is the situation in France? Rev Prat. 2009 Oct 20;59:1048-50 |
| - | Benesch M, Wardelmann E, Ferrari A, Brennan B, Verschuur A. Gastrointestinal stromal tumors (GIST) in children and adolescents: A comprehensive review of the current literature. Pediatr Blood Cancer. 2009;53:1171-9 |
| - | Bernard F, Bordigoni P, Simeoni MC, Barlogis V, Contet A, Loundou A, Thuret I, Leheup B, Chambost H, Play B, Auquier P, Michel G. Height growth during adolescence and final height after haematopoietic SCT for childhood acute leukaemia: the impact of a conditioning regimen with BU or TBI. Bone Marrow Transplant. 2009;43:637-42 |
| - | Bernard F, Gelsi-Boyer V, Murati A, Giraudier S, Trouplin V, Adélaïde J, Rey, J, Olschwang S, Vainchenker W, Chaffanet M, Vey N, Mozziconacci MJ, Birnbaum D. Alterations of NFIA in chronic malignant myeloid diseases. Leukemia 2009; 23:583-5. |
| - | Boelens JJ, Rocha V, Aldenhoven M, Wynn R, O'Meara A, Michel G, Ionescu I, Parikh S, Prasad VK, Szabolcs P, Escolar M, Gluckman E, Cavazzana-Calvo M, Kurtzberg J; EUROCORD, Inborn error Working Party of EBMT and Duke University. Risk factor analysis of outcomes after unrelated cord blood transplantation in patients with hurler syndrome. Biol Blood Marrow Transplant. 2009;15:618-25 |
| - | Bourdeaut F, de Carli E, Timsit S, Coze C, Chastagner P, Sarnacki S, Delattre O, Peuchmaur M, Rubie H, Michon J; Neuroblastoma Committee of the Société Française des Cancers et Leucémies de l'Enfant et de l'Adolescent. VIP hypersecretion as primary or secondary syndrome in neuroblastoma: A retrospective study by the Société Française des Cancers de l'Enfant (SFCE). Pediatr Blood Cancer. 2009;52:585-90 |
| - | Brosselin P, Rudant J, Orsi L, Leverger G, Baruchel A, Bertrand Y, Nelken B, Robert A, Michel G, Margueritte G, Perel Y, Mechinaud F, Bordigoni P, Hemon D, Clavel J. Childhood acute leukemia and residence next to gas stations and automotive repair garages: the ESCALE study (SFCE*). Occup Environ Med. 2009 15 |
| - | Conter C, Carrie C, Bernier V, Geoffray A, Pagnier A, Gentet JC, Lellouch-Tubiana A, Chabaud S, Frappaz D. Intracranial ependymomas in children: society of pediatric oncology experience with postoperative hyperfractionated local radiotherapy. Int J Radiat Oncol Biol Phys. 2009;74:1536-42 |
| - | Fabre A, Roquelaure B, Lacoste C, André N, Sarles J, Breton A, Martinez-Vinson C, Cezard JP, Colomb V, Goulet O, Levy N, Badens C. Exclusion of EGFR, HRAS, DSP, JUP, CTNNB1, PLEC1, and EPPK1 as functional candidate genes in 7 families with syndromic diarrhoea. J Pediatr Gastroenterol Nutr. 2009;48:501-3 |
| - | Guitton C, Garçon L, Cynober T, Gauthier F, Tchernia G, Delaunay J, Leblanc T, Thuret I, Bader-Meunier B. Hereditary spherocytosis: guidelines for the diagnosis and management in Children. Arch Pediatr. 2009;16:556-8 |
| - | Hermans C, Altisent C, Batorova A, Chambost H, de Moerloose P, Karafoulidou A, Klamroth R, Richards M, White B, Dolan G. Replacement therapy for invasive procedures in patients with haemophilia: literature review, European survey and recommendations. Haemophilia. 2009;15:639-58 |
| - | Jagt CT, Zuckermann M, Ten Kate F, Taminiau JA, Dijkgraaf MG, Heij H, De Kraker J, Verschuur AC. Veno-occlusive disease as a complication of preoperative chemotherapy for Wilms tumor: A clinico-pathological analysis. Pediatr Blood Cancer. 2009;53:1211-5 |
| - | Khen-Dunlop N, Castanet M, Picard C, André N, pour la Société Française de Recherche en Pédiatrie. La Société Francophone de Recherche en Pédiatrie : une société menacée ? Arch Ped. 2009;16:313-5 |
| - | Magerus-Chatinet A, Stolzenberg MC, Loffredo MS, Neven B, Schaffner C, Ducrot N, Arkwright PD, Bader-Meunier B, Barbot J, Blanche S, Casanova JL, Debré M, Ferster A, Fieschi C, Florkin B, Galambrun C, Hermine O, Lambotte O, Solary E, Thomas C, Le Deist F, Picard C, Fischer A, Rieux-Laucat F. FAS-L, IL-10, and double-negative CD4- CD8- TCR alpha/beta+ T cells are reliable markers of autoimmune lymphoproliferative syndrome (ALPS) associated with FAS loss of function. Blood. 2009 26;113:3027-30 |
| - | Meunier S, Trossaërt M, Berger C, Borel-Derlon A, Dirat G, Donadel-Claeyssens S, Durin Assolant A, Guérois C, Lutz P, Rafowicz A, Rothschild C, Chambost H, pour le groupe prophylaxie CoMETH. Long term prophylaxis for severe haemophilia A and B children to prevent haemophiliac arthropathy. Arch Ped. 2009;16:1571-8 |
| - | Milano-Bausset E, Gaudart J, Rome A, Coze C, Gentet JC, Padovani L, Lacarelle B, André N. Retrospective comparison of neutropenia in children with Ewing sarcoma treated with chemotherapy and granulocyte colony-stimulating factor (G-CSF) or pegylated G-CSF. Clin Ther. 2009;31 Pt 2:2388-95 |
| - | Morange PE, Trigui N, Frere C, Chambost H, Pouymayou C, Boucly C, Juhan-Vague I, de Mazancourt P. Molecular characterization of a novel mutation in the Factor XIII A subunit gene associated with a severe defect : importance of prophylactic substitution. Blood Coagulation & Fibrinolysis. 2009;20:605-6 |
| - | Moreau T, Bardin F, Barlogis V, Le Deist F, Chabannon C, Tonnelle C. Hematopoietic engraftment of XLA bone marrow CD34(+) cells in NOG/SCID mice. Cytotherapy. 2009;11:198-205 |
| - | Oberlin O, Fawaz O, Rey A, Niaudet P, Ridola V, Orbach D, Bergeron C, Defachelles AS, Gentet JC, Schmitt C, Rubie H, Munzer M, Plantaz D, Deville A, Minard V, Corradini N, Leverger G, de Vathaire F. Long-term evaluation of Ifosfamide-related nephrotoxicity in children. J Clin Oncol. 2009;27:5350-5. |
| - | Padovani L, André N, Carrie C, Muracciole X. Childhood and adult medulloblastoma: what difference?. Cancer Radiother. 2009;13:530-5 |
| - | Padovani L, Huchet A, Claude L, Bernier V, Quetin P, Mahe M, Laprie A, Kerr C, Bondiau PY, Delarue A, Coze C, Gibon D, Barteau C, Maire JP, Carrie C, Muracciole X. Inter-clinician variability in making dosimetric decisions in pediatric treatment: a balance between efficacy and late effects. Radiother Oncol. 2009;93:372-6 |
| - | Perret-Court A, Coulibaly B, Ranque S, Bouvier C, Lena G, Coze C, Verschuur A. Intradural dirofilariasis mimicking a Langerhans cell histiocytosis tumor. Pediatr Blood Cancer. 2009;53:485-7 |
| - | Ridola V, Fawaz O, Aubier F, Bergeron C, de Vathaire F, Pichon F, Orbach D, Gentet JC, Schmitt C, Dufour C, Oberlin O. Testicular function of survivors of childhood cancer: a comparative study between ifosfamide- and cyclophosphamide-based regimens. Eur J Cancer. 2009;45:814-8 |
| - | Rome A, André N, Scavarda D, Gentet JC, De Paula AM, Padovani L, Pasquier E. Metronomic chemotherapy-induced bilateral subdural hematoma in a child with meningeal carcinomatosis. Pediatr Blood Cancer. 2009;53:246-7 |
| - | Salas S, Jézéquel P, Campion L, Deville JL, Chibon F, Bartoli C, Gentet JC, Charbonnel C, Gouraud W, Voutsinos-Porche B, Brouchet A, Duffaud F, Figarella-Branger D, Bouvier C. Molecular characterization of the response to chemotherapy in conventional osteosarcomas: predictive value of HSD17B10 and IFITM2. Int J Cancer. 2009 15;125:851-60 |
| - | Thuret I, Barlogis V, Michel G. [Current concepts in the management of transfusional iron overload]. Arch Pediatr. 2009;16:559-61 |
| - | Thuret I, Chaix ML, Tamalet C, Reliquet V, Firtion G, Tricoire J, Rabaud C, Frange P, Aumaître H, Blanche S. Raltegravir, etravirine and r-darunavir combination in adolescents with multidrug-resistant virus. AIDS. 2009;23:2364-6 |
| - | Thuret I, Hacini M, Pégourié-Bandelier B, Gardembas-Pain M, Bisot-Locard S, Merlat-Guitard A, Bachir D. Socio-psychological impact of infused iron chelation therapy with deferoxamine in metropolitan France: ISOSFER study results. Hematology. 2009;14:315-22 |
| - | Vuorenmaa K, Salah IB, Barlogis V, Chambost H, Drancourt M. Mycobacterium colombiense and Pseudotuberculous Lymphadenopathy. Emerg Infect Dis. 2009;15:619-620 |
| - | Willemze R, Rodrigues CA, Labopin M, Sanz G, Michel G, Socié G, Rio B, Sirvent A, Renaud M, Madero L, Mohty M, Ferra C, Garnier F, Loiseau P, Garcia J, Lecchi L, Kögler G, Beguin Y, Navarrete C, Devos T, Ionescu I, Boudjedir K, Herr AL, Gluckman E, Rocha V; Eurocord-Netcord and Acute Leukaemia Working Party of the EBMT. KIR-ligand incompatibility in the graft-versus-host direction improves outcomes after umbilical cord blood transplantation for acute leukemia. Leukemia. 2009;23:492-500 |
| - | Amigou A, Sermage-Faure C, Orsi L, Leverger G, Baruchel A, Bertrand Y, Nelken B, Robert A, Michel G, Margueritte G, Perel Y, Mechinaud F, Borgigoni P, Hémon D, Clavel J. Road traffic and childhood leukaemia: the ESCALE study (SFCE). Environ Health Perspect. 2010,119:566-72 |
| - | André N, Leblond P, Verschuur A. [Specificity of paediatric oncology pharmacology]. Bull Cancer. 2010;97:191-8 |
| - | André N, Pasquier E. Can drug driven dependency deprivation effect can be used as a therapeutical tools in tuberculosis? Intern J Tuber Lung Dis. 2010;14:1212 |
| - | André N, Padovani L, Verschuur A. Metronomic chemotherapy: Back to the future! Drug News Perspect. 2010;23:143-51 |
| - | André N, Verschuur A, Rossler J, Sterba J. Anti-angiogenic therapies for children with cancer. Curr Cancer Drug Targets. 2010;10:879-89 |
| - | Carcao M, Chambost H, Ljung R. Best practice prophylaxis in haemophilia: evaluation of current treatment strategies. Haemophilia. 2010;S2;162:4-9 |
| - | Chambost H. Assessing risk factors: prevention of inhibitors in haemophilia. Haemophilia. 2010;16 S2:10-15 |
| - | Chambost H, Suzan F, on behalf of FrancCoag Network. Epidemiology of hereditary bleeding disorders: input of FranceCoag Network. Arch Pediatr. 2010;17:618-9 |
| - | Chambost H. Prophylaxis in patients with haemophilia: introduction. Haemophilia. 2010;16 S2:1-3 |
| - | Ciccolini J, Dahan L, André N, Evrard A, Duluc M, Blesius A, Yang C, Giacometti S, Brunet C, Raynal C, Ortiz A, Frances N, Iliadis A, Duffaud F, Seitz JF, Mercier C. Cytidine deaminase residual activity in serum is a predictive marker of early severe toxicities in adults after gemcitabine-based chemotherapies. J Clin Oncol. 2010;28:160-5 |
| - | De Paula AM, André N, Fernandez C, Coulibaly B, Scavarda D, Lena G, Bouvier C. Solitary, extracutaneous, skull-based juvenile xanthogranuloma. Pediatr Blood Cancer 2010;55:380-2. |
| - | Guilhaumou R, Solas C, Rome A, Giocanti M, Andre N, Lacarelle B. Validation of an electrospray ionization LC/MS/MS method for quantitative analysis of vincristine in human plasma samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2010;878:423-7 |
| - | Kashanskiy S, André N. Paediatric mesothelioma: Is there the such a disease ? Bull Cancer. 2010;97:571-6 |
| - | Mancini J, Baumstarck-Barrau K, Simeoni MC, Grob JJ, Michel G, Tarpin C, Loundou AD, Lambert A, Clément A, Auquier P. Quality of life in a heterogeneous sample of caregivers of cancer patients: an in-depth interview study. Eur J Cancer Care . 2010, 20:483-92 |
| - | Monpoux F, Chambost H, Haouy S, Benadiba J, Sirvent N. Recombinant activated factor VII in paediatric practice. Universal hemostatic agent? Arch Pediatr. 2010;17:1210-9 |
| - | Moreau E, André N, Coze C, Padovani L, Mercier C, Ciccolini J. Can CDA deficiency explain tumour lysis syndrome in a child with neuroblastoma receiving gemcitabine? Pediatr Blood Cancer. 2010;54:781-2 |
| - | Nicollas R, Rome A, Belaïch H, Roman S, Volk M, Gentet JC, Michel G, Triglia JM. Head and neck manifestation and prognosis of Langerhans' cell histiocytosis in children. Int J Pediatr Otorhinolaryngol. 2010;74:669-73 |
| - | Paillard C, Salmon A, Curtillet C, David A, Halle P, Cachin F, Bordigoni P, Michel G, Rousseau R, Dore E, Isfan F, Merlin E, Rochette E, Demeocq F, Kanold J. Evidence of a clinical response at one yr after reduced-intensity allogeneic hematopoietic stem cell transplantation in heavily pretreated adolescents with aggressive refractory Hodgkin's lymphoma. Pediatr Transplant. 2010;14:109-14 |
| - | Pasquier E, Kavallaris M, André N. Metronomic chemotherapy: new rationale for new directions? Nature Reviews Clinical Oncology. 2010;7:455-65 |
| - | Pasquier E, André N. New therapeutic advances and perspectives in tumour angiogenesis. Curr Cancer Drug Targets.2010;10:877-8 |
| - | Pérez B, Mechinaud F, Galambrun C, Ben Romdhane N, Isidor B, Philip N, Derain-Court J, Cassinat B, Lachenaud J, Kaltenbach S, Salmon A, Désirée C, Pereira S, Menot ML, Royer N, Fenneteau O, Baruchel A, Chomienne C, Verloes A,Cavé H. Germline mutations of the CBL gene define a new genetic syndrome with predisposition to juvenile myelomonocytic leukaemia. J Med Genet. 2010;47:686-91 |
| - | Réguerre Y, Lacour B, André N, Claude L, Hameury F, Lavrand F, Kalfa N, Peuchmaur M, Orbach D. Epidemiology and management of rare paediatric tumours within the framework of the French Society for Children Cancer. Bull Cancer. 2010;97:1041-5 |
| - | Rubie H, Geoerger B, Frappaz D, Schmitt A, Leblond P, Ndiaye A, Aerts I, Le Deley MC, Gentet JC, Paci A, Chastagner P, Dias N, Djafari L, Pasquet M, Chatelut E, Landman-Parker J, Corradini N, Vassal G. Phase I study of topotecan in combination with temozolomide (TOTEM) in relapsed or refractory paediatric solid tumours. Eur J Cancer. 2010;46:2763-70 |
| - | Rudant J, Orsi L, Menegaux F, Petit A, Baruchel A, Bertrand Y, Lambilliotte A, Robert A, Michel G, Margueritte G, Tandonnet J, Mechinaud F, Bordigoni P, Hémon D, Clavel J. Chilhood Acute Leukemia, Early Common Infections, and Allergy: The ESCALE Study. Am J Epidemiol. 2010,172:1015-27 |
| - | Schiff M, Ogier de Baulny H, Bard G, Barlogis V, Hamel C, Moat SJ, Odent S, Shortland G, Touati G, Giraudier S. Should transcobalamin deficiency be treated aggressively? J Inherit Metab Dis. 2010;33:223-9 |
| - | Sterba J, Pavelka Z, André N, Ventruba J, Skotakova J, V Bajciova V, Bronisova D, Dubska L, Valik D. Second complete remission in a child with relapsed medulloblastoma induced by metronomic chemotherapy and subsequent progression shortly after chemotherapy cessation. Pediatr Blood Cancer. 2010;54:616-7 |
| - | Thuret I, Sarles J, Merono F, Suzineau E, Collomb J, Lena-Russo D, Levy N, Bardakdjian J, Badens C. Neonatal screening for sickle cell disease in France: evaluation of the selective process. J Clin Pathol. 2010;63:548-51 |
| - | Thuret I, Pondarré C, Loundou A, Steschenko D, Girot R, Bachir D, Rose C, Barlogis V, Donadieu J, de Montalembert M, Hagege I, Pegourie B, Berger C, Micheau M, Bernaudin F, Leblanc T, Lutz L, Galactéros F, Siméoni MC, Badens C. Complications and treatment of patients with {beta}-thalassemia in France: results of the national registry. Haematologica. 2010;95:724-9 |
| - | Verschuur AC, Vujanic GM, Van Tinteren H, Jones KP, de Kraker J, Sandstedt B. Stromal and epithelial predominant Wilms tumours have an excellent outcome: the SIOP 93 01 experience. Pediatr Blood Cancer. 2010;55:233-8 |
| - | Zacharoulis S, Ashley S, Moreno L, Gentet JC, Massimino M, Frappaz D. Treatment and outcome of children with relapsed ependymoma: a multi-institutional retrospective analysis. Childs Nerv Syst. 2010;26:905-11 |
| - | Zwaan CM, Kearns P, Caron H, Verschuur A, Riccardi R, Boos J, Doz F, Geoerger B, Morland B, Vassal G; ITCC European consortium. The role of the 'innovative therapies for children with cancer' (ITCC) European consortium. Cancer Treat Rev. 2010;36:328-34 |
© Faculté de Médecine de Marseill l Mentions légales l Mise à jour du 27 février 2012